Interrelationships Between Iron and Lead Absorption in Iron-Deficient Mice
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چکیده
منابع مشابه
Olfactory ferric and ferrous iron absorption in iron-deficient rats.
The absorption of metals from the nasal cavity to the blood and the brain initiates an important route of occupational exposures leading to health risks. Divalent metal transporter-1 (DMT1) plays a significant role in the absorption of intranasally instilled manganese, but whether iron uptake would be mediated by the same pathway is unknown. In iron-deficient rats, blood (59)Fe levels after int...
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We used a unique animal model, the hypotransferrinemic (Htx) mouse, to examine the role of transferrin (Tf) in gastrointestinal iron uptake. Despite the absence of Tf, Htx animals hyperabsorb iron. Transfusion of red blood cells sufficient to normalize the hematocrit and reticulocyte count resulted in a return of iron absorption to normal values. These studies indicate that Tf does not play an ...
متن کاملBlood lead levels in iron-deficient and noniron-deficient adults.
Iron deficiency (ID) has been reported to increase lead absorption. This relationship has been investigated in detail in children but not in adults. This study was designed to investigate whether blood lead levels are significantly higher in iron-deficient adults. ID-parameters (haemoglobin, mean corpuscular volume, mean corpuscular haemoglobin, serum iron, total iron-binding capacity, iron-bin...
متن کاملIron Status in Newborns Born to Iron-Deficient Mothers
Background: Iron deficiency anemia is one of the important problems during pregnancy. Iron deficiency has several adverse effects on pregnant women and their newborns. Objective: To determine the status of iron store in newborns born to mothers with iron deficiency anemia. Methods: In a cross-sectional study, 90 mothers were categorized into three groups according to their pre-delivery hemoglo...
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The observations that the peptide hormone gastrin interacts with transferrin in vitro and that circulating gastrin concentrations are increased in the iron-loading disorder hemochromatosis suggest a possible link between gastrin and iron homeostasis. This study tested the hypothesis that gastrin and iron status are interrelated by measurement of iron homeostasis in mice and humans with abnormal...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1979
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(79)80080-3